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Accelerating drug discovery

PUBLIC CALL

EDF在线老虎机March 30, 2020

March 30, 2020

Let’s fight COVID-19 together

Help us fight coronavirus by joining the COVID Moonshot (), an initiative that aims to rapidly develop antiviral therapeutics via crowdsourcing. COVID Moonshot has experimentally obtained over 60 high quality structures of fragments bound to the main protease and is now asking for your ideas on which molecules we should make and test.

The second round of submission will close on Thursday, April 2nd midnight Pacific Time, but there will be more. Read more >>

172 723 Fragment compounds
including 27 000 Covalent fragments available from stock

Fragments

EDF在线老虎机PRESS RELEASE

Mar 11, 2020

March 11, 2020

Enamine to be the exclusive supplier of Astex’ MiniFrag Library

Enamine Ltd. and Astex Pharmaceuticals (UK) have cooperated to provide wide access to Astex’ MiniFrag library, an efficient Fragment-based Drug Discovery tool for identification of hot and warm spots of protein targets. The Library is readily available from Enamine in any suitable format, including dry samples or assay-ready high concentration (1M, 100mM) aqueous soaks in containers of preferred type. The detected MiniFrag hits can be followed-up with a wide range of stock available and synthetically feasible derivatives as well as with building blocks for introduction of the relevant structural features for lead optimization. Read more >>

Reach out to new chemical space breaking the availability bias:
14 000 000 000 molecules and beyond

REAL compounds

NEWS

Mar 10, 2020

March 10, 2020

An open-source drug discovery platform enables ultra-large virtual screens

We are delighted to announce another application of Enamine REAL database recently published in Nature. This paper is a result of the collaborative effort of scientists from Enamine and the leading academic institutions from the USA and Germany. Read More >>

Ref.: Nature 2020, in press

Run HTS directly at Enamine or have your copy from
Ever-expanding collection of 3 million compounds

Screening Libraries & HTS

NEWS

Dec 12, 2019

EDF在线老虎机December 12, 2019

New RNA targeted library has been created!

The number of targets, the number of diseases that one could go after by targeting RNA, is almost unimaginable, says Matt Disney, a chemist at the Scripps Research Institute.

In response to growing interest and recent advancements in targeting RNA our experts designed dedicated library of small molecules predicted to bind to RNA targets. In contrast to the classical protein targets and disease treatment, drugging RNA reveals absolutely new way to treat and prevent different disorders.

Our freshly-made library is ready for fast shipment within a week in various custom formats.

RNA Library contains 8 960 compounds. EDF在线老虎机Read more >>

The world's largest collection of building blocks in stock:
186 910 and counting

EDF在线老虎机New Building Blocks

EDF在线老虎机Scientific research and development of techniques for the synthesis of organic compounds

High Fidelity Fragments

High Fidelity Library

Fragments of high MedChem tractability  

REAL Database

The largest enumerated database of synthetically feasible molecules

Functional Compounds

Impurity Reference Standards
 

Covalent Fragments

Covalent Fragments

Diverse covalent warheads with balanced reactivity

2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from February 2020

Recent News

  • 30 March 2020   News

    EDF在线老虎机Let’s fight COVID-19 together

    An international group of scientists from academia and industry, including Enamine, is trying to help combat COVID-19. This effort began when Chinese scientists worked rapidly to determine the structure of the novel SARS‑CoV‑2 main protease (Mpro), which triggered a massive crystal-based fragment screen at the XChem facility at UK’s Diamond Light Source. For more details, please visit . With the same urgency, the scientists are now trying to progress these data towards what is desperately needed: effective, easy-to-make anti-COVID drugs .

  • 11 March 2020   Press Releases

    Enamine to be the exclusive supplier of Astex’ MiniFrag ...

    Enamine Ltd。 and Astex Pharmaceuticals (UK) have cooperated to provide wide access to Astex’ MiniFrag library, an efficient Fragment-based Drug Discovery tool for identification of hot and warm spots of protein targets。 The Library is readily available from Enamine in any suitable format, including dry samples or assay-ready high concentration (1M, 100mM) aqueous soaks in containers of preferred type。 The detected MiniFrag hits can be followed-up with a wide range of stock available and synthetically feasible derivatives as well as with building blocks for introduction of the relevant structural features for lead optimization。

    Read press release

  • 10 March 2020   News

    An open-source drug discovery platform enables ultra-large virtual screens

    We are delighted to announce another application of Enamine REAL database recently published in . This paper is a result of the collaborative effort of scientists from Enamine and the leading academic institutions from the USA and Germany.

Upcoming events

  • TBC

    Exhibitor, Sponsoring

    Eindhoven, Netherlands

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    Delegates, Sponsoring

    Surrey, UK

  • Cancelled

    Delegates

    Paris, France

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